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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC63
All Species:
11.52
Human Site:
S544
Identified Species:
19.49
UniProt:
Q9UGP8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGP8
NP_009145.1
760
87997
S544
T
P
V
L
L
P
Q
S
K
Q
Q
K
Q
K
Q
Chimpanzee
Pan troglodytes
XP_001148185
760
87976
S544
T
P
V
L
L
P
Q
S
K
Q
Q
K
Q
K
Q
Rhesus Macaque
Macaca mulatta
XP_001091991
689
79874
T509
G
E
T
N
K
N
R
T
K
G
G
W
Q
Q
K
Dog
Lupus familis
XP_532252
850
96553
S634
T
P
V
P
L
P
Q
S
K
Q
Q
K
Q
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHE0
760
87823
A544
T
T
V
P
L
P
Q
A
K
Q
Q
K
Q
K
Q
Rat
Rattus norvegicus
NP_001101107
727
83574
G544
T
T
V
P
L
P
Q
G
K
Q
Q
K
Q
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511532
775
89598
A559
A
P
V
P
L
S
Q
A
K
Q
Q
K
Q
K
Q
Chicken
Gallus gallus
XP_419802
759
87965
P543
V
P
P
S
L
Q
P
P
K
Q
Q
K
Q
K
Q
Frog
Xenopus laevis
NP_001088542
754
87189
Q544
Q
P
L
P
Q
Q
K
Q
I
K
Q
K
Q
A
N
Zebra Danio
Brachydanio rerio
XP_002666271
754
86861
G542
V
T
Q
Q
Q
A
K
G
D
K
A
K
Q
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648111
753
85835
T556
A
A
T
T
A
T
I
T
A
S
E
D
Q
A
A
Honey Bee
Apis mellifera
XP_395961
751
87148
N548
K
K
F
T
S
T
K
N
A
Q
T
Q
L
Q
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793617
800
91710
K533
G
N
K
P
K
P
K
K
Q
Q
E
K
E
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P14906
663
75326
Q484
E
P
Q
D
F
E
S
Q
R
D
P
F
A
M
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
89.3
88.3
N.A.
96.1
91.8
N.A.
86.8
91.5
83.4
72.3
N.A.
44
42.3
N.A.
40.8
Protein Similarity:
100
99.8
89.8
89.1
N.A.
98.5
94.2
N.A.
91.8
95.7
91.8
84.7
N.A.
63.6
62.3
N.A.
59
P-Site Identity:
100
100
13.3
93.3
N.A.
80
80
N.A.
73.3
60
26.6
13.3
N.A.
6.6
6.6
N.A.
26.6
P-Site Similarity:
100
100
40
93.3
N.A.
86.6
80
N.A.
80
60
46.6
26.6
N.A.
20
33.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
0
8
8
0
15
15
0
8
0
8
22
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
8
8
0
8
0
0
0
% D
% Glu:
8
8
0
0
0
8
0
0
0
0
15
0
8
0
8
% E
% Phe:
0
0
8
0
8
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
15
0
0
0
0
0
0
15
0
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% I
% Lys:
8
8
8
0
15
0
29
8
58
15
0
72
0
58
8
% K
% Leu:
0
0
8
15
50
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
8
0
8
0
8
0
8
0
0
0
0
0
0
15
% N
% Pro:
0
50
8
43
0
43
8
8
0
0
8
0
0
0
0
% P
% Gln:
8
0
15
8
15
15
43
15
8
65
58
8
79
15
50
% Q
% Arg:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
8
8
8
22
0
8
0
0
0
0
8
% S
% Thr:
36
22
15
15
0
15
0
15
0
0
8
0
0
0
0
% T
% Val:
15
0
43
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _